Since carney et al reported a rare thyroid lesion termed hyalinizing trabecular adenoma hta presenting with characteristics of a trabecular growth pattern and hyalinizing stroma in 1987, controversies concerning the classification of this entity have arisen. Trabecular tissue definition of trabecular tissue by. Indicators of malignancy of canine adrenocortical tumors. However, cytological diagnosis of htt remains elusive and misleading because. Aging is a complex process, and the effects of aging are myriad and insidious, leading to progressive deterioration of various organs, including the skeleton. This tumor typically behaves in a benign fashion but malignant cases have been reported. Trabecular pattern definition of trabecular pattern by. The tissue undergoes a series of steps before it reaches the diagnosis. Jonathan swift 1667 1745 benign fibroosseous lesions a group of lesions in which normal bone is replaced initially by fibrous connective tissue over time, the lesion is infiltrated by osteoid. Hyalinizing trabecular carcinoma of the thyroid gland. Figure 3 shows the agerelated changes of trabecular bone at the proximal tibia. This tumor is known to share morphological and architectural similarities with paraganglioma and medullary thyroid carcinoma, as well as the nuclear features and retptc1 translocations of papillary thyroid carcinoma.
Oct 25, 2007 hyalinizing trabecular tumor htt is a rare thyroid tumor of follicular cell origin with a trabecular pattern of growth and marked intratrabecular hyalinization. A pathology report contains a description of the microscopical characteristics of the tumor tissue, including both tumor cells and how the tumor invades into healthy tissues and finally if the tumor appears to be completely removed. Analysis of trabecular distribution of the proximal femur. The second pattern acinar pseudoglandular and shows tumour cells organized into glandlike structures representing. Mar 28, 2012 in 1987, carney et al described a rare thyroid tumor termed hyalinizing trabecular adenoma presenting characteristics consisting of a trabecular growth pattern and hyalinizing stroma. To achieve this it is important that the tissue must be prepared in such a manner. Subsequently, samples were processed for histology and evaluated for oarsi grade. Anatomically, the upper end of the femur is a common site for osteoporosis. The histopathology of colorectal cancer of the adenocarcinoma type involves analysis of tissue taken from a biopsy or surgery. Jonathan swift 1667 1745 benign fibroosseous lesions. Sadowsky department of orthodontics, school of dentistry of the university of the witwatersrand.
Manufacturing a wooden or metal shape or model used in a foundry to make a mould the juxtaposition of repetitive elements in a design, organized so as to. Because the observed expression of serotonin associated with a trabecular pattern of growth with stromal fibrosis is similar to that seen in ileal carcinoids. In group i, two main sets of trabeculae were observed. Computerized tomography ct scans of eight patients group iii were studied to determine the real.
However, cytological diagnosis of htt remains elusive and misleading because of overlapping. All simulated images were compared to full bone cortical a nd trabecular bone image similar to a dental radiograph. Histopathology images of hepatocellular carcinoma by. Thyroid tumors, hyalinizing trabecular tumor, trabecular pattern. Read hyalinizing trabecular carcinoma of thyroid gland, histopathology on deepdyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips. Most believe it to be a unique entity, whereas others have argued that it is a variant of papillary carcinoma. Trabecular bmd and bvtv of the proximal tibia show agerelated decreases in women and men 5153. Trabecular bone pattern factor how is trabecular bone pattern factor abbreviated. Read hyalinizing trabecular carcinoma of the thyroid gland, histopathology on deepdyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips.
Background the trabecular architecture of the olecranon and proximal ulna has not been studied in detail. These endothelial cells classically stain for cd34. Whether htt is a benign tumor or a variant of papillary thyroid carcinoma ptc is still unclear. Histopathology of the trabecular meshwork in glaucoma. Trabecular pattern article about trabecular pattern by. The tubular pattern shows similar cytology with the tumor cells arranged in nests surrounded by variable amounts of eosinophilic, often hyalinized stroma. The features extracted using gabor filter, wavelet transform and fractal. Merkel cell carcinoma is aggressive and associated with high mortality. Hyalinizing trabecular tumour htt is a rare thyroid neoplasm with a trabecular growth pattern, marked intratrabecular hyalinization and nuclear features of papillary thyroid carcinoma ptc. Vascular invasion was determined using the surgical report as well as histologic examination of the tumor. Hyalinizing trabecular tumor htt is a rare thyroid gland neoplasm that was first described in 1987 by carney et al. This file contains additional information such as exif metadata which may have been added by the digital camera, scanner, or software program used to create or digitize it. A read is counted each time someone views a publication summary such as the title, abstract, and list of authors, clicks on a figure, or views or downloads the fulltext. It is a tumor of follicular derivation with peculiar nuclear, architectural, histochemical, and immunohistochemical features.
A trabecula plural trabeculae, from latin for small beam is a small, often microscopic, tissue element in the form of a small beam, strut or rod that supports or anchors a framework of parts within a body or organ. Hyalinizing trabecular tumor htt is a rare unique but controversial thyroid neoplasm, characterized by prominent trabecular growth pattern and stromal hyalinization. The elderly population has substantially increased worldwide. Serotonin expression in pancreatic neuroendocrine tumors. All the tumors examined were at least partially surrounded by. Hyalinizing trabecular tumor of the thyroid gland is a rare neoplasm of follicular origin that is characterized by an encapsulated nodule, a prominent trabecular growth pattern, and stromal hyalinization. The case presented is an injury with corresponding to the characteristics described in the literature. Each bone parameter and oarsi grade was compared to assess structural adaptation of bone with oa severity.
Ann arbor, michigan the histopathology of the trabecular meshwork is an important part of glaucoma re search since the cause of most glaucomas is suspected in or around this corneoscleral fil tration meshwork. In pathology, trabecular is encountered with some frequency. Trabecular bone pattern factor how is trabecular bone. Anterior and middle bundles support the subarticular. Trabecular pattern of proximal femur refers to the five groups of trabeculae that are demonstrable within the femoral head and neck. Mar 30, 2010 hyalinizing trabecular tumour of the thyroiddifferential expression of distinct mirnas compared with papillary thyroid carcinoma. Trabecular pattern analysis of proximal femur radiographs. Definition of trabecular pattern in the financial dictionary by free online english dictionary and encyclopedia. The predetermined singh indexes of trabecular pattern are used to justify the classification result. Recent advances in the classification of hepatocellular carcinoma.
Follicular adenoma follicular adenoma is defined as a benign encapsulated tumor with follicular cell differentiation showing a uniform pattern throughout the confine nodule figure 1a. Begin by identifying the trabeculae, the spongy network of bone tissue in the center of the bone. Trabecular definition of trabecular by medical dictionary. Hyalinizing trabecular tumor htt of the thyroid is a rare neoplasm that was first described by carney in 1987. The surface of trabeculae are covered by a thin layer of inactive cells called endosteum. Because htn and papillary thyroid carcinoma ptc share similar histopathological. Serotonin expression in pancreatic neuroendocrine tumors correlates with a trabecular histologic pattern and large duct involvement. Hyalinizing trabecular tumor of the thyroid gland 2018.
A trabecula generally has a mechanical function, and is usually composed of dense collagenous tissue such as the trabecula of the spleen. Occurs in most cases in patients aged below 15 years, and the maxilla is the most involved bone. Histopathology techniques histopathology definition. It is a branch of pathology which deals with the study of disease in a tissue section. The first set of trabeculae consists of three bundles, which arise from the anterior cortex.
The classic pattern of ck20 expression is dotlike and paranuclear. Trabecular bone specimens from the medial compartment of the proximal tibial metaphyses have been examined with microct and scanning electron microscopy 5153. Tumors were considered to have a trabecular pattern when at least one third of the tumor consisted of this pattern. Occasionally, the stroma component is increased, compressing the tumor cells into thin strands, forming a trabecular pattern. Agerelated changes in trabecular and cortical bone. The fibrous capsule varies in thickness, but is usually thin. Human males and females differed in the pattern of trabecular spacing with males having more uniform trabecular spacing across the joint surface. Agerelated bone loss and resultant osteoporosis in the elderly population increase the risk for fractures and morbidity. Histopathology of colorectal adenocarcinoma wikipedia. Objectives by the end of this session you should be able to differentiate between most of the patterns in histopathology. The trabecular pattern in the upper end of femur is analyzed on the basis of the presence or absence, the relative number and density of the trabeculae, trabecular group and also by the grading of trabeculae. Association between subchondral bone structure and. Trabecular pattern definition of trabecular pattern by the.
The assessment of osteoporosis can be performed by observing and analyzing the trabecular patterns recorded in proximal femur radiographs. Hyalinizing trabecular tumour htt is a rare thyroid neoplasm of follicular cell origin characterised by a trabecular growth pattern and prominent intratrabecular and intertrabecular hyalinisation. Jun 24, 2016 hyalinizing trabecular tumor of the thyroid gland is a rare neoplasm of follicular origin that is characterized by an encapsulated nodule, a prominent trabecular growth pattern, and stromal hyalinization. A radiological study on the trabecular pattern in the upper. A total of 99 elderly women were scanned by mdct including. Trabecular pattern financial definition of trabecular pattern. Multidetector computed tomography mdct was used in order to assess the trabecular distribution of proximal femur and its relationship with hip fragility fractures. Dreyer dental research unit of the university of the witwatersrand and the south african medical research council p. Trabecular bone this slide shows trabecular, or spongy bone. Trabecular pattern article about trabecular pattern by the. Merkel cell carcinoma primarily affects the sun exposed skin of elderly males and preferentially the head and neck region.
Mar 01, 2008 read hyalinizing trabecular carcinoma of the thyroid gland, histopathology on deepdyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips. Hcc is more common in males than in females and mostly occurs in developing countries. Hyalinizing trabecular tumor htt is a rare thyroid tumor of follicular cell origin with a trabecular pattern of growth and marked intratrabecular hyalinization. The trabecular juvenile ossifying fibroma who type is a rare fibroosseous begnin injury with biologic aggressive behavior, and unknown etiology. Basic concept trabecula is a supportive and connective tissue element which form in cancellous bone. Despite the fact that a radiograph is a two dimensional. Trabecular pattern trabeculae may be straight or curved giving organoid pattern elongated to polygonal cells with variable pleomorphism. Analysis of trabecular distribution of the proximal femur in. These peculiar histological features allow the prompt recognition of this neoplasm in surgical specimens. To compare the expression pattern of five micrornas mirnas 146b. Trabecular pattern analysis of proximal femur radiographs for.
Hyalinizing trabecular tumour of the thyroiddifferential. Therefore, the trabecular pattern in the upper end of femur is analyzed on the basis of the presence or absence, the relative number and density of the trabeculae, trabecular group and. Hepatocellular carcinoma hcc is the sixth most common type of cancer and with about 9. Welldifferentiated hcc, however, may be difficult to distinguish from normal hepatic parenchyma or hepatocellular adenomas. Major issues and pitfalls in the diagnosis of hcc are highlighted. Htt may htt may be commonly mistaken for papillary carcinoma, medullary carcinoma or paraganglioma. In subsequent reports, the observed nuclear features and ret alterations led this tumor to be linked to papillary carcinoma. It is a thyroid tumor of a follicular origin and is characterized by trabecular pattern and intratrabecular hyalinization. We undertook a primarily cadaveric study aiming to link with the theory of biomechanics. It is a thyroid tumor of a follicular origin and is characterized by.
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